First to Eibar in La Liga, and then a tie against Chelsea in the Champions League.
While Barcelona remain unbeaten in La Liga this season, Eibar have lost only one of their last 12 games in the competition, a 1-0 defeat to Atletico at Ipurua in January.
The win against Eibar means Barcelona lead La Liga with 62 points and extend their record to 19 wins, five draws, and zero losses.
Depending on Barcelona's result in Eibar, Atletico Madrid could have the chance to move to within four points of the top of the table when they entertain Athletic Club Bilbao on Sunday afternoon.
Just before the hour mark, Ivan Rakitic - a former Sevilla captain - broke their resistance before Lionel Messi and Luis Suarez netted two apiece in a stunning demolition job in the final thirty minutes.
However, in the 66th minute they were sent down to ten men after Orellana received his second yellow card for dissent after he punched the ball away after Diop was penalised for a challenge on Sergio Busquets.
However, Alba sealed the match in the last minute after.
Barcelona needed to put down a marker after two disappointing league results but found it hard to play through an Eibar side who pressed from the off, and saw Jose Angel nod over the bar inside a minute.
Not many teams in the world will cost €300 million to assemble, but that's how much Barcelona have spent on Ousmane Dembele and Coutinho.
But having passed their Eibar exam, Tuesday's trip to Stamford Bridge represents an altogether tougher test for Valverde's side. Dembele has had awful luck with injuries and Coutinho is only just getting started, having joined in a club-record €160m deal from Liverpool in January.
Lionel Messi continues to amaze week in and week out, and on Saturday it came as a passer.
Suarez's goal came against the flow of the match.
Suarez returned the compliment when he found Messi but the Argentinian hit the woodwork.
Eibar know exactly how to play in the small ground with the stands virtually on top of the pitch and very often with the wet conditions that await Barca on Saturday. Five of those victories were 1-0, including each of the last two.
Madrid travel after their 3-1 Champions League win at home to Paris Saint Germain in a game they turned around in the last 7 minutes and they too will be flying.
Even after Orellana's red card, Eibar still posed a threat. They were expected to fight near the bottom of the standings this year, but they have stunned the world time and time again, and now sit in seventh place in the standings with 35 points.
Opponents can not plan for Lionel Messi, they must simply react to the "unpredictable" Barcelona superstar, says former team-mate Deco.